If you've beaten BioShock multiple times and know every Little Sister and locked door by heart, the . Just be ready for seeds where you fight a Bouncer with only the Wrench and a single EVE Hypo.
Because I found the Shotgun late (it was in Ryan’s office, of all places), I learned to appreciate the level design on a cellular level. I know exactly which tables offer cover. I know the patrol routes. The randomizer strips away your power fantasy and forces you to play BioShock like a survival horror game. bioshock randomizer
A great feature for a would be "Unstable Splice" (or Plasmid Logic Randomization). Beyond Rapture: How the BioShock Randomizer Breathes New